Varying coefficients model with measurement error.

نویسندگان

  • Liang Li
  • Tom Greene
چکیده

We propose a semiparametric partially varying coefficient model to study the relationship between serum creatinine concentration and the glomerular filtration rate (GFR) among kidney donors and patients with chronic kidney disease. A regression model is used to relate serum creatinine to GFR and demographic factors in which coefficient of GFR is expressed as a function of age to allow its effect to be age dependent. GFR measurements obtained from the clearance of a radioactively labeled isotope are assumed to be a surrogate for the true GFR, with the relationship between measured and true GFR expressed using an additive error model. We use locally corrected score equations to estimate parameters and coefficient functions, and propose an expected generalized cross-validation (EGCV) method to select the kernel bandwidth. The performance of the proposed methods, which avoid distributional assumptions on the true GFR and residuals, is investigated by simulation. Accounting for measurement error using the proposed model reduced apparent inconsistencies in the relationship between serum creatinine and GFR among different clinical data sets derived from kidney donor and chronic kidney disease source populations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Sieve Estimation of Constant and Time-Varying Coefficients in Nonlinear Ordinary Differential Equation Models by Considering Both Numerical Error and Measurement Error.

This article considers estimation of constant and time-varying coefficients in nonlinear ordinary differential equation (ODE) models where analytic closed-form solutions are not available. The numerical solution-based nonlinear least squares (NLS) estimator is investigated in this study. A numerical algorithm such as the Runge-Kutta method is used to approximate the ODE solution. The asymptotic...

متن کامل

Modeling and Forecasting Iranian Inflation with Time Varying BVAR Models

This paper investigates the forecasting performance of different time-varying BVAR models for Iranian inflation. Forecast accuracy of a BVAR model with Litterman’s prior compared with a time-varying BVAR model (a version introduced by Doan et al., 1984); and a modified time-varying BVAR model, where the autoregressive coefficients are held constant and only the deterministic components are allo...

متن کامل

Simultaneous Monitoring of Multivariate Process Mean and Variability in the Presence of Measurement Error with Linearly Increasing Variance under Additive Covariate Model (RESEARCH NOTE)

In recent years, some researches have been done on simultaneous monitoring of multivariate process mean vector and covariance matrix. However, the effect of measurement error, which exists in many practical applications, on the performance of these control charts is not well studied. In this paper, the effect of measurement error with linearly increasing variance on the performance of ELR contr...

متن کامل

Semiparametric approaches for joint modeling of longitudinal and survival data with time-varying coefficients.

We study joint modeling of survival and longitudinal data. There are two regression models of interest. The primary model is for survival outcomes, which are assumed to follow a time-varying coefficient proportional hazards model. The second model is for longitudinal data, which are assumed to follow a random effects model. Based on the trajectory of a subject's longitudinal data, some covariat...

متن کامل

An application of Measurement error evaluation using latent class analysis

‎Latent class analysis (LCA) is a method of evaluating non sampling errors‎, ‎especially measurement error in categorical data‎. ‎Biemer (2011) introduced four latent class modeling approaches‎: ‎probability model parameterization‎, ‎log linear model‎, ‎modified path model‎, ‎and graphical model using path diagrams‎. ‎These models are interchangeable‎. ‎Latent class probability models express l...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Biometrics

دوره 64 2  شماره 

صفحات  -

تاریخ انتشار 2008